亚海生物 Yahai Biotech

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Biotechnology, transforming life

YaHai Biotech Co., Ltd. is a company primarily engaged in the promotion and application of scientific and technological services.

The company focuses on advancing cutting-edge molecular biology technologies and applying pharmaceutical and chemical innovations in life science research and human health. It is committed to becoming a global producer and service provider of biological products. AsiaGene Biotech’s business spans various fields including biopharmaceuticals, gene research (such as siRNA and mimics), animal models, pharmaceutical raw materials, and DNA testing. It provides molecular tools, gene sequencing, and bioinformatics support to research universities, scientific institutions, hospitals, pharmaceutical R&D companies, and agricultural enterprises worldwide.

In oncology testing, the company relies on a comprehensive molecular pathology platform to offer precise molecular pathology testing products and services for solid tumors to patients, hospitals, and pharmaceutical companies. Focusing on molecular tool development, deep gene sequencing, and big data analysis and interpretation, AsiaGene continuously develops international-grade tumor gene testing and molecular therapy products. It also offers personalized oncology treatment solutions, including drug guidance, dynamic monitoring, and genetic susceptibility testing for cancers.

In the field of genetic testing, the company has developed a range of services based on next-generation sequencing (NGS) technology, including preconception genetic testing, newborn genetic screening, and personal genome analysis. These services support the application of genomics in human health, particularly in reproductive health and personal genomics, and are accompanied by professional genetic counseling for clients.

Short Tandem Repeat (STR)
Single Nucleotide Polymorphism (SNP)

DNA identification is a technique that determines identity, biological relationships, or resolves legal disputes by analyzing an individual’s DNA sequence. It is widely used in areas such as criminal investigations, paternity testing, inheritance claims, and the search for missing persons. DNA samples can be obtained from various sources, including blood, saliva, hair, and skin cells. By analyzing specific DNA markers, scientists can accurately match relationships or identities between different samples. With its high precision and low error rate, DNA identification has become a vital tool in modern forensic science, medicine, and genetic research.

Types of Genetic Disorders
Central Dogma of Molecular Biology

Genetic testing for hereditary diseases is a technique that analyzes an individual’s genome to identify mutations or variations associated with inherited disorders. This testing can help predict the risk of potential genetic diseases, enable early diagnosis, and provide personalized health management recommendations. By collecting samples such as blood or saliva, the test results can reveal an individual’s susceptibility to conditions like hereditary cancers, cardiovascular diseases, and metabolic disorders. Genetic testing not only supports early intervention and disease prevention, but also offers scientific guidance for family planning, helping individuals who carry certain genetic mutations understand the potential health risks to their offspring.

Multistep (or Multistage/Multiple-Mutation) Carcinogenesis Process

Tumor genetic testing and medication guidance is a technique that analyzes genetic mutations in tumor cells to help physicians develop precise treatment plans for cancer patients. By extracting tumor tissue or blood samples from the patient, the test identifies specific gene mutations, variations, or expression changes associated with cancer, revealing the molecular characteristics of the tumor. Based on the results, doctors can select the most appropriate targeted therapies, immunotherapies, or chemotherapy drugs tailored to the genetic profile of the patient’s tumor, aiming to improve treatment efficacy and reduce side effects. In addition, tumor genetic testing can help predict the risk of disease recurrence, provide personalized medication guidance, and enhance the patient’s quality of life and prognosis.

miRNA

We specialize in efficient and safe viral RNA vector technology, offering one-stop solutions for vaccine development, gene therapy, cell engineering, and functional gene screening. Our platform integrates state-of-the-art biosafety level III production facilities, automated high-throughput purification systems, and stringent quality control processes. We provide customized RNA vectors such as lentivirus and retrovirus with titers up to 10¹⁰ TU/mL.

Our services include sequence optimization and synthesis, vector construction, packaging and purification, functional validation, and IND application support. We offer three product grades—GMP-grade, research-grade, and lyophilized formulations—to meet the full range of needs from laboratory research to preclinical and clinical production.

With core strengths in fast delivery, low endotoxin levels, and batch-to-batch consistency, we help our partners shorten R&D timelines and accelerate the translation of innovative achievements.

We offer a one-stop CRISPR-Cas9 solution: intelligent sgRNA design, Cas9 protein/mRNA/RNP production, plasmid-lentivirus-AAV-LNP delivery, and NGS-based off-target detection. With editing efficiency ≥90% and off-target rate <0.1%, our standard products are delivered within 7 days. We support projects from basic research to IND-level clinical applications, helping customers accelerate gene function studies and the development of cell and gene therapies.

Team Introduction

We are an interdisciplinary biotechnology team with core members from the fields of molecular genetics, clinical medicine, and bioinformatics. Our services span DNA paternity testing, rare genetic disease screening, precision oncology drug guidance based on tumor genetics, viral RNA vector development, and comprehensive CRISPR-Cas9 gene editing solutions.

The team holds multiple proprietary patents in GMP-grade laboratory platforms and high-throughput sequencing data interpretation algorithms. To date, we have served over 300 medical and research institutions, committed to accelerating the safe and efficient translation of genetic technologies into clinical and industrial applications.